Billy West is best known as the star of Futurama, Ren & Stimpy, Doug, The New Woody Woodpecker Show and the voice of Bugs Bunny in Space Jam!

On Futurama he is the voice of Fry, Professor Farnsworth, Dr. Zoidberg, Zapp Brannigan, Leo Wong, Richard Nixon's head, Ipgee, M5438, The Educational films narrator, Gearshift, Humorbot 5.0, The Transition Announcer, Judge Whitey, The Galactic Entity, Sinclair 2K and more. He was the voice of Stimpy in The Ren & Stimpy Show from 1991-1996, and he provided the voice of Ren from 1993–1996.  Billy performed other characters on the series as well, such as Mr. Horse and the "Announcer/Salesman". He was the voice of Doug in the long running Doug series, and has been the voice of both Bugs Bunny and Elmer Fudd for several Looney Tunes films and video games, including Space Jam. He was the star The New Woody Woodpecker Show, voicing Woody Woodpecker, Wally Walrus and Dr. Doug Nutts.

Billy launched his career in the early 1980s performing daily comedic routines on Boston's WBCN. He left the radio station to work on the short-lived revival of Beany and Cecil. He was also a writer and cast member on The Howard Stern Show during the early to mid 1990s, where he gained nationwide fame with his impersonations of Larry Fine and late Cincinnati Reds owner Marge Schott. In 1998, West starred in the direct-to-video film Scooby-Doo on Zombie Island as Shaggy Rogers, becoming the second person to portray the character. He was the voice of Zim in the original pilot for Nickelodeon's Invader Zim and is also the voice of "Red" in numerous M&M commercials as well as the 3-D movie "I Lost my M in Vegas". West reprises his role as Elmer Fudd in Cartoon Network's series The Looney Tunes Show.

In 2004, West voiced the classic character Popeye in the 75th anniversary film Popeye's Voyage: The Quest for Pappy, and made his live-action film debut in Mark Hamill's Comic Book: The Movie. He also appeared in a cameo in Garfield: The Movie.

Other films featuring West's vocal talents include Joe's Apartment, Cats & Dogs, Olive, the Other Reindeer, TMNT, The Proud Family Movie, and three Tom and Jerry direct-to-video movies.